| Mutation | S450T >View Structure< | MuteXt @ GPCRDB |
Region | TM3 |
General number GPCRDB / Ballesteros-Extended | 326
3.36 |
| Receptor | LSHR Human | Swiss-Prot
Crossreferences at GPCRDB |
| Phenotype | Constitutivity (compared to WT): Unknown
Cell-surface expression (%WT): Unknown
Binding affinity of native hormone: Unknown
|
| Additional comments | Predicted non-constitutive activity | |
| Download | Download the flat text file of this mutant (more info here) | |
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| Reference #1 |
Theoretical study on mutation-induced activation of the luteinizing hormone receptor.
Fanelli F
J Mol Biol. 2000 Mar 10;296(5):1333-51. | Pubmed |