|Mutation||V221G >>View Structure<<
||General number GPCRDB / Ballesteros-Extended||0
Crossreferences at GPCRDB
|Phenotype||Constitutivity (compared to WT): Unknown|
Cell-surface expression (%WT): Unknown
Binding affinity of native hormone: Unknown
|Additional comments||A novel mutation in exon8 of FSHR was identified in a woman with primary amenorrhea whose ovaries reacted to high-dose hMG treatment.
Natural occuring mutation.|
|Download||Download the flat text file of this mutant (more info here)|
||A novel mutation in exon8 of the follicle-stimulating hormone receptor in a woman with primary amenorrhea.|
Nakamura Y, Maekawa R, Yamagata Y, Tamura I, Sugino N
Gynecol Endocrinol. 2008 Dec;24(12):708-12.